Fracture Healing in Patients With HIV in South Africa: A Prospective Cohort Study.

ABSTRACT:

Background

HIV reduces bone mineral density, mineralization, and turnover and may impair fracture healing.

Setting

This prospective cohort study in South Africa investigated whether HIV infection was associated with impaired fracture healing after trauma.

Methods

All adults with acute tibia and femur fractures who underwent intermedullary (IM) nailing for fracture fixation between September 2017 and December 2018, at 2 tertiary hospitals, were followed up for a minimum of 12 months postoperatively. The primary outcome was delayed bone union at 6 months (defined by the radiological union scoring system for the tibia score <9), and the secondary outcome was nonunion (defined as radiological union scoring system for the tibia score <9) at 9 months. Multivariable logistic

SUBMITTER: Graham SM 

PROVIDER: S-EPMC8263144 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature