In-vivo impact of common cosmetic preservative systems in full formulation on the skin microbiome.

ABSTRACT: Preservatives play an essentially role in ensuring that cosmetic formulations remain safe for use via control of microbial contamination. Commonly used preservatives include organic acids, alcohols and phenols and these play an essential role in controlling the growth of bacteria, fungi and moulds in substrates that can potentially act as a rich food source for microbial contaminants. Whilst the activity of these compounds is clear, both in vitro and in formulation, little information exists on the potential impact that common preservative systems, in full formulation, have on the skin's resident microbiome. Dysbiosis of the skin's microbiome has been associated with a number of cosmetic conditions but there currently are no in vivo studies investigating the potential for preservative ingr

SUBMITTER: Murphy B 

PROVIDER: S-EPMC8263265 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature