Harmonisation of PET/CT contrast recovery performance for brain studies.

ABSTRACT:

Purpose

In order to achieve comparability of image quality, harmonisation of PET system performance is imperative. In this study, prototype harmonisation criteria for PET brain studies were developed.

Methods

Twelve clinical PET/CT systems (4 GE, 4 Philips, 4 Siemens, including SiPM-based "digital" systems) were used to acquire 30-min PET scans of a Hoffman 3D Brain phantom filled with ~ 33 kBq·mL^-1 [¹⁸F]FDG. Scan data were reconstructed using various reconstruction settings. The images were rigidly coregistered to a template (voxel size 1.17 × 1.17 × 2.00 mm³) onto which several volumes of interest (VOIs) were defined. Recovery coefficients (RC) and grey matter to white matter ratios (GMWMr) were derived for eroded (denoted in the text by su

SUBMITTER: Verwer EE 

PROVIDER: S-EPMC8263427 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature