Association of heart rate with cardiovascular events and mortality in hypertensive and normotensive population: a nationwide prospective cohort study.

ABSTRACT:

Background

Cardiovascular disease is the leading cause of death worldwide. We assessed the association of baseline heart rate with cardiovascular events and mortality in hypertensive and normotensive populations using a prospective urban and rural epidemiology cohort study in China.

Methods

A total of 29,554 individuals were involved in our analysis, distributed equally between groups of normotensive and hypertensive. The primary outcomes were myocardial infarction, stroke, major cardiovascular diseases, and cardiovascular mortality. Cox frailty models were utilized to estimate hazard ratios for cardiovascular outcomes, and restricted cubic splines were used to explore the shape of the association between baseline heart rate and cardiovascular mortality.

Results

Durin

SUBMITTER: Wang Y 

PROVIDER: S-EPMC8263883 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature