Earlier diagnosis improves COVID-19 prognosis: a nationwide retrospective cohort analysis.

ABSTRACT:

Background

Risk of adverse outcomes in COVID-19 patients by stratifying by the time from symptom onset to confirmed diagnosis status is still uncertain.

Methods

We included 1,590 hospitalized COVID-19 patients confirmed by real-time RT-PCR assay or high-throughput sequencing of pharyngeal and nasal swab specimens from 575 hospitals across China between 11 December 2019 and 31 January 2020. Times from symptom onset to confirmed diagnosis, from symptom onset to first medical visit and from first medical visit to confirmed diagnosis were described and turned into binary variables by the maximally selected rank statistics method. Then, survival analysis, including a log-rank test, Cox regression, and conditional inference tree (CTREE) was conducted, regarding whether patients pr

SUBMITTER: Chen YJ 

PROVIDER: S-EPMC8263884 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature