Soluble ST2 and mixed venous oxygen saturation for prediction of mortality in patients with pulmonary hypertension.

ABSTRACT:

Background

Although soluble suppression of tumorigenicity-2 (sST2) has been identified as a clinical biomarker for pulmonary hypertension (PH) by previous studies, the implication of sST2 combined with hemodynamic parameters in PH has not been well studied. This study aimed to evaluate the relationship between sST2 and hemodynamic parameters and to evaluate the predictive value of sST2 for mortality in patients with PH.

Methods

One hundred eighty-four incident patients with PH and 14 healthy controls were retrospectively enrolled by Shanghai Pulmonary Hospital for this retrospective study. After all patients underwent right heart catheterization, blood samples were collected and serum sST2 concentration was assessed by the Presage™ ST2 assay. Kaplan-Meier curve and Cox regre

SUBMITTER: Sun Y 

PROVIDER: S-EPMC8264676 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature