The role of gender in non-small cell lung cancer: a narrative review.

ABSTRACT: The role of gender in the development, treatment and prognosis of thoracic malignancies has been underappreciated and understudied. While most research has been grounded in tobacco-related malignancies, the incidence of non-smoking related lung cancer is on the rise and disproportionately affecting women. Recent research studies have unveiled critical differences between men and women with regard to risk factors, timeliness of diagnosis, incongruent screening practices, molecular and genetic mechanisms, as well as response to treatment and survival. These studies also highlight the increasingly recognized need for targeted therapies that account for variations in the response and complications as a function of gender. Similarly, screening recommendations continue to evolve as the role of g

SUBMITTER: Baiu I 

PROVIDER: S-EPMC8264700 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature