Strategies for Nonpolar Aerosol Collection and Heavy Metals Analysis of Inhaled Cannabis Products.

ABSTRACT: The rapid growth of inhalable cannabis concentrates raises questions about the safety of acute and chronic exposure to these aerosol mixtures. Due to the nonpolar nature of the aerosol mixture created from cannabis vapor cartridges, traditional aqueous-based capture methods used in e-cigarette or tobacco cigarette studies for analysis of metals are insufficient. Moreover, hydrophobic cannabis concentrates are not miscible with dilute aqueous acids and therefore not ideal for metal spiking unlike electronic nicotine delivery systems. This study describes a method of spiking nonaqueous matrices with aqueous metals standards to investigate aerosolization and recovery of the metals. It also compares various methods for nonpolar aerosol capture and subsequent analysis of 10 metals (As, Cd, Co,

SUBMITTER: Mallampati SR 

PROVIDER: S-EPMC8264932 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature