Quantification of regurgitation in mitral valve prolapse with four-dimensional flow cardiovascular magnetic resonance.

ABSTRACT:

Background

Four-dimensional cardiovascular magnetic resonance (CMR) flow assessment (4D flow) allows to derive volumetric quantitative parameters in mitral regurgitation (MR) using retrospective valve tracking. However, prior studies have been conducted in functional MR or in patients with congenital heart disease, thus, data regarding the usefulness of 4D flow CMR in case of a valve pathology like mitral valve prolapse (MVP) are scarce. This study aimed to evaluate the clinical utility of cine-guided valve segmentation of 4D flow CMR in assessment of MR in MVP when compared to standardized routine CMR and transthoracic echocardiography (TTE).

Methods

Six healthy subjects and 54 patients (55 ± 16 years; 47 men) with MVP were studied. TTE severity grading used a multiparametr

SUBMITTER: Spampinato RA 

PROVIDER: S-EPMC8265147 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature