Thunor: visualization and analysis of high-throughput dose-response datasets.

ABSTRACT: High-throughput cell proliferation assays to quantify drug-response are becoming increasingly common and powerful with the emergence of improved automation and multi-time point analysis methods. However, pipelines for analysis of these datasets that provide reproducible, efficient, and interactive visualization and interpretation are sorely lacking. To address this need, we introduce Thunor, an open-source software platform to manage, analyze, and visualize large, dose-dependent cell proliferation datasets. Thunor supports both end-point and time-based proliferation assays as input. It provides a simple, user-friendly interface with interactive plots and publication-quality images of cell proliferation time courses, dose-response curves, and derived dose-response metrics, e.g. IC50, includ

SUBMITTER: Lubbock ALR 

PROVIDER: S-EPMC8265171 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature