Comparison of the Glaesserella parasuis Virulence in Mice and Piglets.

ABSTRACT: In this study, we compared the virulence of the most common serovars of Glaesserella parasuis in China, serovars 4, 5, 12, and 13 (36 strains in total) in BALB/c mice and piglets. In mice, the median lethal doses (LD₅₀s) of the four serovars were roughly 9.80 × 10⁷-4.60 × 10⁹ CFU, 2.10 × 10⁸-8.85 × 10⁹ CFU, 4.81 × 10⁷-7.01 × 10⁹ CFU, and 1.75 × 10⁸-8.45 × 10⁸ CFU, respectively. Serovar 13 showed the strongest virulence, followed by serovar 4, serovar 12, and serovar 5, but a significant difference in virulence was only observed between serovars 5 and 13. The virulence of strains of the same serovars differed significantly in piglets. Virulent and attenuated strains were present in all

SUBMITTER: Qi B 

PROVIDER: S-EPMC8265781 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature