Post-discharge thrombosis and bleeding in medical patients: A novel risk score derived from ubiquitous biomarkers.

ABSTRACT:

Background

Some hospitalized medical patients experience venous thromboembolism (VTE) following discharge. Prophylaxis extended beyond hospital discharge (extended duration thromboprophylaxis [EDT]) may reduce this risk. However, EDT is costly and can cause bleeding, so selecting appropriate patients is essential. We formerly reported the performance of a mortality risk prediction score (Intermountain Risk Score [IMRS]) that was minimally predictive of 90-day hospital-associated venous thromboembolism (HA-VTE) and major bleeding (HA-MB). We used the components of the IMRS to calculate de novo risk scores to predict 90-day HA-VTE (HA-VTE IMRS) and major bleeding (HA-MB IMRS).

Methods

From 45 669 medical patients we randomly assigned 30 445 to derive the HA-VTE IMRS and the HA

SUBMITTER: Woller SC 

PROVIDER: S-EPMC8265782 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature