The Comparison of Different Constitutive Laws and Fiber Architectures for the Aortic Valve on Fluid-Structure Interaction Simulation.

ABSTRACT: Built on the hybrid immersed boundary/finite element (IB/FE) method, fluid-structure interaction (FSI) simulations of aortic valve (AV) dynamics are performed with three different constitutive laws and two different fiber architectures for the AV leaflets. An idealized AV model is used and mounted in a straight tube, and a three-element Windkessel model is further attached to the aorta. After obtaining ex vivo biaxial tensile testing of porcine AV leaflets, we first determine the constitutive parameters of the selected three constitutive laws by matching the analytical stretch-stress relations derived from constitutive laws to the experimentally measured data. Both the average error and relevant R-squared value reveal that the anisotropic non-linear constitutive law with exponential

SUBMITTER: Cai L 

PROVIDER: S-EPMC8266211 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature