Bile Reflux Gastropathy and Functional Dyspepsia.

ABSTRACT:

Background/aims

The pathoetiology of functional dyspepsia remains unclear; one mechanism could be chemical gastropathy from chronic bile reflux. We aim to examine the association of bile reflux gastropathy with functional dyspepsia and identify predisposing factors.

Methods

In a retrospective study, patients with functional dyspepsia (Rome III) who completed symptom assessment, esophagogastroduodenoscopy, and biopsies were categorized into 3 groups; bile gastropathy (BG), non-bile gastropathy (NBG), and no gastropathy (NG). Demographics, symptoms, endoscopy, and motility data were compared between groups. Multivariate analysis identified clinical factors associated with BG.

Results

Of 262 patients (77.5% female), 90 had BG, 121 had NBG, and 51 had NG. Baseline demogra

SUBMITTER: Lake A 

PROVIDER: S-EPMC8266494 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature