Testosterone Increases the Emission of Ultrasonic Vocalizations With Different Acoustic Characteristics in Mice.

ABSTRACT: Testosterone masculinizes male sexual behavior through an organizational and activational effects. We previously reported that the emission of ultrasonic vocalizations (USVs) in male mice was dependent on the organizational effects of testosterone; females treated with testosterone in the perinatal and peripubertal periods, but not in adults, had increased USV emissions compared to males. Recently, it was revealed that male USVs have various acoustic characteristics and these variations were related to behavioral interactions with other mice. In this regard, the detailed acoustic characteristic changes induced by testosterone have not been fully elucidated. Here, we revealed that testosterone administered to female and male mice modulated the acoustic characteristics of USVs. There was no

SUBMITTER: Kikusui T 

PROVIDER: S-EPMC8267093 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature