Retrospective comparison of high-resolution computed tomography of eosinophilic granulomatosis with polyangiitis with severe asthma.

ABSTRACT:

Background

Eosinophilic granulomatosis with polyangiitis (EGPA) is often misdiagnosed as severe asthma due to their similar clinical presentations. We compared the pulmonary radiologic features of EGPA to those of severe asthma by high-resolution computed tomography (HRCT) in order to early diagnose EGPA.

Methods

We retrospectively reviewed clinical records and HRCT findings of 96 patients with EGPA and 82 patients with severe asthma who were seen at our hospital from 2011 to 2017. We used a semi-quantitative grading system to evaluate radiological findings. A radiological only and a clinical-radiological model were used to differentiate EGPA from severe asthma.

Results

Bronchial wall thickening, air trapping, tree-in-bud opacities, bronchial mucus plugging, bronchiec

SUBMITTER: Lin X 

PROVIDER: S-EPMC8267300 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature