Functional Contributions of the Arcuate Fasciculus to Language Processing.

ABSTRACT: Current evidence strongly suggests that the arcuate fasciculus (AF) is critical for language, from spontaneous speech and word retrieval to repetition and comprehension abilities. However, to further pinpoint its unique and differential role in language, its anatomy needs to be explored in greater detail and its contribution to language processing beyond that of known cortical language areas must be established. We address this in a comprehensive evaluation of the specific functional role of the AF in a well-characterized cohort of individuals with chronic aphasia (n = 33) following left hemisphere stroke. To evaluate macro- and microstructural integrity of the AF, tractography based on the constrained spherical deconvolution model was performed. The AF in the left and right hemisph

SUBMITTER: Ivanova MV 

PROVIDER: S-EPMC8267805 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature