Direct visualization of drug behaviors in the upper GI tract via magnetically controlled capsule endoscopy.

ABSTRACT:

Background and aims

Actual behaviors of drugs in the upper GI tract are not well elucidated. We assess the feasibility of magnetically controlled capsule endoscopy (MCE) in direct and real-time visualization of oral drug behaviors in the stomach.

Methods

From November 2019 to December 2019, 9 patients with a recent history of upper GI symptoms and 10 healthy volunteers were enrolled in this study. Participants swallowed magnetically controlled capsules to examine the whole stomach. After baseline examination, participants ingested dyed sucralfate gel, and MCE recorded the adhesion time, retention time, and distribution area of sucralfate gel. Outcomes included behaviors of sucralfate gel, safety, and satisfaction assessment of the procedures.

Results

Adhesion time of

SUBMITTER: Wang YC 

PROVIDER: S-EPMC8267953 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature