Discrimination capability of pretest probability of stable coronary artery disease: a systematic review and meta-analysis suggesting how to improve validation procedures.

ABSTRACT:

Objective

Externally validated pretest probability models for risk stratification of subjects with chest pain and suspected stable coronary artery disease (CAD), determined through invasive coronary angiography or coronary CT angiography, are analysed to characterise the best validation procedures in terms of discriminatory ability, predictive variables and method completeness.

Design

Systematic review and meta-analysis.

Data sources

Global Health (Ovid), Healthstar (Ovid) and MEDLINE (Ovid) searched on 22 April 2020.

Eligibility criteria

We included studies validating pretest models for the first-line assessment of patients with chest pain and suspected stable CAD. Reasons for exclusion: acute coronary syndrome, unstable chest pain, a history of myocardial inf

SUBMITTER: Mincarone P 

PROVIDER: S-EPMC8268916 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature