Projection of Gut Microbiome Pre- and Post-Bariatric Surgery To Predict Surgery Outcome.

ABSTRACT: Bariatric surgery is often the preferred method to resolve obesity and diabetes, with ∼800,000 cases worldwide yearly and high outcome variability. The ability to predict the long-term body mass index (BMI) change following surgery has important implications for individuals and the health care system in general. Given the tight connection between eating habits, sugar consumption, BMI, and the gut microbiome, we tested whether the microbiome before any treatment is associated with different treatment outcomes, as well as other intakes (high-density lipoproteins [HDL], triglycerides, etc.). A projection of the gut microbiome composition of obese (sampled before and after bariatric surgery) and lean patients into principal components was performed, and the relation between this projection and

SUBMITTER: Ben Izhak M 

PROVIDER: S-EPMC8269264 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature