Identifying the Critical Threshold for Long-Term Pediatric Neurological Hospitalizations of the Offspring in Preterm Delivery.

ABSTRACT: We opted to investigate whether a critical threshold exists for long-term pediatric neurological morbidity, and cerebral palsy (CP), in preterm delivery, via a population-based cohort analysis. Four study groups were classified according to their gestational age at birth: 24-27.6, 28-31.6, 32-36.6 weeks and term deliveries, evaluating the incidence of long-term hospitalizations of the offspring due to neurological morbidity. Cox proportional hazard models were performed to control for confounders. A Kaplan-Meier survival curve was used to compare the cumulative neurological morbidity incidence for each group. A total of 220,563 deliveries were included: 0.1% (118) occurred at 24-27.6 weeks of gestation, 0.4% (776) occurred at 28-31.6 weeks of gestation, 6% (13,308) occurred at 32-36.6 week

SUBMITTER: Zer S 

PROVIDER: S-EPMC8269302 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature