Microencapsulation of nattokinase from fermentation by spray drying: Optimization, comprehensive score, and stability.

ABSTRACT: Nattokinase from fermentation has recently gained more attention due to its beneficial effects on cardiovascular system. However, the instability of free nattokinase limits its application. The aim of the study was to develop a spray-drying microencapsulation process to obtain the nattokinase powder with high activity, high quality, and strong storage stability. Hence, the microencapsulation process of nattokinase from fermentation by spray drying was optimized. Experiments of single-factor and response surface methodology were used to assess the comprehensive scores and nattokinase activities. According to single-factor and response surface methodology results, optimum parameters of microencapsulation process of the nattokinase power by spray drying were 30% of mass ratio of wall material

SUBMITTER: Li G 

PROVIDER: S-EPMC8269611 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature