Abnormalities in cortical pattern of coherence in migraine detected using ultra high-density EEG.

ABSTRACT: Individuals with migraine generally experience photophobia and/or phonophobia during and between migraine attacks. Many different mechanisms have been postulated to explain these migraine phenomena including abnormal patterns of connectivity across the cortex. The results, however, remain contradictory and there is no clear consensus on the nature of the cortical abnormalities in migraine. Here, we uncover alterations in cortical patterns of coherence (connectivity) in interictal migraineurs during the presentation of visual and auditory stimuli and during rest. We used a high-density EEG system, with 128 customized electrode locations, to compare inter- and intra-hemispheric coherence in the interictal period from 17 individuals with migraine (12 female) and 18 age- and gender-matched hea

SUBMITTER: Chamanzar A 

PROVIDER: S-EPMC8269966 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature