A Systematic Review of Proton Therapy for the Management of Nasopharyngeal Cancer.

ABSTRACT:

Purpose

With improved technology, more patients with nasopharyngeal cancer (NPC) are receiving definitive treatment with proton therapy, which allows greater sparing of dose to normal tissues without compromising efficacy. As there is no randomized data, the purpose of this study was to systematically review the available literature on proton therapy in this setting, focusing on the toxicity endpoints.

Materials and methods

A systematic search using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines was conducted in 5 databases: PubMed, Embase, SCOPUS, Web of Science, and the Cochrane Central Register of Controlled Trials. A total of 491 studies were found on the topic of NPC and proton therapy. Following independent study selection by 2 i

SUBMITTER: Lee A 

PROVIDER: S-EPMC8270076 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature