Patient-Reported Outcomes after Intensity-Modulated Proton Therapy for Oropharynx Cancer.

ABSTRACT:

Purpose

To report patient-reported outcomes (PROs) derived from the Functional Assessment of Cancer Therapy-Head and Neck (FACT-HN) tool, in patients with oropharynx cancer (OPC) treated with intensity-modulated proton therapy (IMPT) in the context of first-course irradiation.

Materials and methods

Patients with locally advanced OPC treated with radical IMPT between 2011 and 2018 were included in a prospective registry. FACT-HN scores were measured serially during and 24 months following IMPT. PRO changes in the FACT-HN scores over time were assessed with mixed-model analysis.

Results

Fifty-seven patients met inclusion criteria. Median age was 60 years (range, 41-84), and 91% had human papillomavirus-associated disease. In total, 28% received induction chemotherapy an

SUBMITTER: Bahig H 

PROVIDER: S-EPMC8270092 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature