Proton Therapy for Major Salivary Gland Cancer: Clinical Outcomes.

ABSTRACT:

Purpose

To report clinical outcomes in terms of disease control and toxicity in patients with major salivary gland cancers (SGCs) treated with proton beam therapy.

Materials and methods

Clinical and dosimetric characteristics of patients with SGCs treated from August 2011 to February 2020 on an observational, prospective, single-institution protocol were abstracted. Local control and overall survival were calculated by the Kaplan-Meier method. During radiation, weekly assessments of toxicity were obtained, and for patients with ≥ 90 days of follow-up, late toxicity was assessed.

Results

Seventy-two patients were identified. Median age was 54 years (range, 23-87 years). Sixty-three patients (88%) received postoperative therapy, and nine patients (12%) were treated defi

SUBMITTER: Hanania AN 

PROVIDER: S-EPMC8270094 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature