Epidemiology and disease burden of sickle cell disease in France: A descriptive study based on a French nationwide claim database.

ABSTRACT:

Context

Sickle cell disease (SCD) is a severe hematological disorder. The most common acute complication of SCD is vaso-occlusive crisis (VOC), but SCD is a systemic disease potentially involving all organs. SCD prevalence estimates rely mostly on extrapolations from incidence-based newborn screening programs, although recent improvements in survival may have led to an increase in prevalence, and immigration could account for a substantial number of prevalent patients in Europe. The primary objective of this study was to estimate SCD prevalence in France.

Methods

A cross-sectional observational study was conducted using a representative sample of national health insurance data. SCD patients followed up in France between 2006 and 2011 were captured through hydroxyurea reimbur

SUBMITTER: Leleu H 

PROVIDER: S-EPMC8270152 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature