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Association between intraoperative fluid balance, vasopressors and graft complications in liver transplantation: A cohort study.


ABSTRACT:

Introduction

Biliary complications following liver transplantation are common. The effect of intraoperative fluid balance and vasopressors on these complications is unknown.

Materials and methods

We conducted a cohort study between July 2008 and December 2017. Our exposure variables were the total intraoperative fluid balance and the use of vasopressors on ICU admission. Our primary outcome was any biliary complication (anastomotic and non-anastomotic strictures) up to one year after transplantation. Our secondary outcomes were vascular complications, primary graft non-function and survival.

Results

We included 562 consecutive liver transplantations. 192 (34%) transplants had a biliary complication, 167 (30%) had an anastomotic stricture and 56 had a non-anastomotic s

SUBMITTER: Lariviere J 

PROVIDER: S-EPMC8270449 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature