Untargeted metabolomics approach to discriminate mistletoe commercial products.

ABSTRACT: Mistletoe (Viscum album L.) is used in German-speaking European countries in the field of integrative oncology linking conventional and complementary medicine therapies to improve quality of life. Various companies sell extracts, fermented or not, for injection by subcutaneous or intra-tumoral route with a regulatory status of anthroposophic medicinal products (European Medicinal Agency (EMA) assessment status). These companies as well as anthroposophical physicians argue that complex matrices composed of many molecules in mixture are necessary for activity and that the host tree of the mistletoe parasitic plant is the main determining factor for this matrix composition. The critical point is that parenteral devices of European mistletoe extracts do not have a standard chemical composition

SUBMITTER: Vanhaverbeke C 

PROVIDER: S-EPMC8270909 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature