Global breast cancer incidence and mortality trends by region, age-groups, and fertility patterns.

ABSTRACT:

Background

Breast cancer (BC) has been increasing globally, though it is unclear whether the increases are seen across all age groups and regions and whether changes in rates can be primarily attributed to decreasing fertility rates. We investigated age-specific trends in BC incidence and mortality from 1990 to 2017, worldwide and by region, and evaluated whether incidence trends are explained by decreases in fertility.

Methods

We used country-level data to examine trends in BC incidence and mortality rates from 1990 to 2017 by region and age group. Linear mixed models were used to estimate age-specific rates from baseline models of year and were compared to fertility-adjusted models for incidence.

Results

The global BC mortality rate increased overall by 0.23% per ye

SUBMITTER: Lima SM 

PROVIDER: S-EPMC8271114 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature