Ontology highlight
ABSTRACT: Background
Research efforts to measure the concept of healthy ageing have been diverse and limited to specific populations. This diversity limits the potential to compare healthy ageing across countries and/or populations. In this study, we developed a novel measurement scale of healthy ageing using worldwide cohorts.Methods
In the Ageing Trajectories of Health-Longitudinal Opportunities and Synergies (ATHLOS) project, data from 16 international cohorts were harmonized. Using ATHLOS data, an item response theory (IRT) model was used to develop a scale with 41 items related to health and functioning. Measurement heterogeneity due to intra-dataset specificities was detected, applying differential item functioning via a logistic regression framework. The model accounted for specificities in model parameters by introducing cohort-specific parameters that rescaled scores to the main scale, using an equating procedure. Final scores were estimated for all individuals and converted to T-scores with a mean of 50 and a standard deviation of 10.Results
A common scale was created for 343 915 individuals above 18 years of age from 16 studies. The scale showed solid evidence of concurrent validity regarding various sociodemographic, life and health factors, and convergent validity with healthy life expectancy (r = 0.81) and gross domestic product (r = 0.58). Survival curves showed that the scale could also be predictive of mortality.Conclusions
The ATHLOS scale, due to its reliability and global representativeness, has the potential to contribute to worldwide research on healthy ageing.
SUBMITTER: Sanchez-Niubo A
PROVIDER: S-EPMC8271194 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Sanchez-Niubo Albert A Forero Carlos G CG Wu Yu-Tzu YT Giné-Vázquez Iago I Prina Matthew M De La Fuente Javier J Daskalopoulou Christina C Critselis Elena E De La Torre-Luque Alejandro A Panagiotakos Demosthenes D Arndt Holger H Ayuso-Mateos José Luis JL Bayes-Marin Ivet I Bickenbach Jerome J Bobak Martin M Caballero Francisco Félix FF Chatterji Somnath S Egea-Cortés Laia L García-Esquinas Esther E Leonardi Matilde M Koskinen Seppo S Koupil Ilona I Mellor-Marsá Blanca B Olaya Beatriz B Pająk Andrzej A Prince Martin M Raggi Alberto A Rodríguez-Artalejo Fernando F Sanderson Warren W Scherbov Sergei S Tamosiunas Abdonas A Tobias-Adamczyk Beata B Tyrovolas Stefanos S Haro Josep Maria JM
International journal of epidemiology 20210701 3
<h4>Background</h4>Research efforts to measure the concept of healthy ageing have been diverse and limited to specific populations. This diversity limits the potential to compare healthy ageing across countries and/or populations. In this study, we developed a novel measurement scale of healthy ageing using worldwide cohorts.<h4>Methods</h4>In the Ageing Trajectories of Health-Longitudinal Opportunities and Synergies (ATHLOS) project, data from 16 international cohorts were harmonized. Using ATH ...[more]