Ontology highlight
ABSTRACT:
SUBMITTER: Bystritskaya E
PROVIDER: S-EPMC8272246 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Bystritskaya Evgeniya E Chernysheva Nadezhda N Stenkova Anna A Guzev Konstantin K Rakin Alexander A Isaeva Marina M
Molecules (Basel, Switzerland) 20210628 13
Here, we investigated general porin regulation in <i>Yersinia pseudotuberculosis</i> 488, the causative agent of Far Eastern scarlet-like fever, in response to sublethal concentrations of antibiotics. We chose four antibiotics of different classes and measured gene expression using qRT-PCR and GFP reporter systems. Our data showed temporal regulation of the general porin genes <i>ompF</i> and <i>ompC</i> caused by antibiotic stress. The porin transcription initially decreased, providing early de ...[more]