Modeling shield immunity to reduce COVID-19 epidemic spread.

ABSTRACT: The COVID-19 pandemic has precipitated a global crisis, with more than 1,430,000 confirmed cases and more than 85,000 confirmed deaths globally as of 9 April 2020^1-4. Mitigation and suppression of new infections have emerged as the two predominant public health control strategies⁵. Both strategies focus on reducing new infections by limiting human-to-human interactions, which could be both socially and economically unsustainable in the long term. We have developed and analyzed an epidemiological intervention model that leverages serological tests^6,7 to identify and deploy recovered individuals⁸ as focal points for sustaining safer interactions via interaction substitution, developing what we term 'shield immunity' at the population scale. The obj

SUBMITTER: Weitz JS 

PROVIDER: S-EPMC8272982 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature