Survival of infants born with esophageal atresia among 24 international birth defects surveillance programs.

ABSTRACT:

Background

Esophageal atresia (EA) affects around 2.3-2.6 per 10,000 births world-wide. Infants born with this condition require surgical correction soon after birth. Most survival studies of infants with EA are locally or regionally based. We aimed to describe survival across multiple world regions.

Methods

We included infants diagnosed with EA between 1980 and 2015 from 24 birth defects surveillance programs that are members of the International Clearinghouse for Birth Defects Surveillance and Research. We calculated survival as the proportion of liveborn infants alive at 1 month, 1- and 5-years, among all infants with EA, those with isolated EA, those with EA and additional anomalies or EA and a chromosomal anomaly or genetic syndrome. We also investigated trends in survi

SUBMITTER: Bell JC 

PROVIDER: S-EPMC8273078 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature