Development of a probability calculator for psychosis risk in children, adolescents, and young adults.

ABSTRACT:

Background

Assessment of risks of illnesses has been an important part of medicine for decades. We now have hundreds of 'risk calculators' for illnesses, including brain disorders, and these calculators are continually improving as more diverse measures are collected on larger samples.

Methods

We first replicated an existing psychosis risk calculator and then used our own sample to develop a similar calculator for use in recruiting 'psychosis risk' enriched community samples. We assessed 632 participants age 8-21 (52% female; 48% Black) from a community sample with longitudinal data on neurocognitive, clinical, medical, and environmental variables. We used this information to predict psychosis spectrum (PS) status in the future. We selected variables based on lasso, random f

SUBMITTER: Moore TM 

PROVIDER: S-EPMC8273212 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature