Changes in Functional Status Among Kidney Transplant Recipients: Data From the Scientific Registry of Transplant Recipients.

ABSTRACT:

Background

With stressors of dialysis prekidney transplantation (KT) and restoration of kidney function post-KT, it is likely that KT recipients experience a decline in functional status while on the waitlist and improvements post-KT.

Methods

We leveraged 224 832 KT recipients from the national registry (SRTR, February 1990-May 2019) with measured Karnofsky Performance Status (KPS, 0%-100%) at listing, KT admission, and post-KT. We quantified the change in KPS from listing to KT using generalized linear models. We described post-KT KPS trajectories using adjusted mixed-effects models and tested whether those trajectories differed by age, sex, race, and diabetes status using a Wald test among all KT recipients. We then quantified risk adverse post-KT outcomes (mortality and a

SUBMITTER: Chu NM 

PROVIDER: S-EPMC8273213 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature