The epidemiology of kidney disease in people of African ancestry with HIV in the UK.

ABSTRACT:

Background

Chronic kidney disease (CKD) is a leading cause of morbidity and mortality globally. The risk of CKD is increased in people of African ancestry and with Human Immunodeficiency Virus (HIV) infection.

Methods

We conducted a cross-sectional study investigating the relationship between region of ancestry (East, Central, South or West Africa) and kidney disease in people of sub-Saharan African ancestry with HIV in the UK between May 2018 and February 2020. The primary outcome was renal impairment (estimated glomerular filtration rate [eGFR] of <60 mL/min/1.73 m²). Secondary outcomes were stage 5 CKD (eGFR <15 ml/min/1.73 m², on dialysis for over 3 months or who had received a kidney transplant), proteinuria (urine protein/creatinine ratio >50 mg/m

SUBMITTER: Hung RKY 

PROVIDER: S-EPMC8273351 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature