Livestock Network Analysis for Rhodesiense Human African Trypanosomiasis Control in Uganda.

ABSTRACT: Background: Infected cattle sourced from districts with established foci for Trypanosoma brucei rhodesiense human African trypanosomiasis (rHAT) migrating to previously unaffected districts, have resulted in a significant expansion of the disease in Uganda. This study explores livestock movement data to describe cattle trade network topology and assess the effects of disease control interventions on the transmission of rHAT infectiousness. Methods: Network analysis was used to generate a cattle trade network with livestock data which was collected from cattle traders (n = 197) and validated using random graph methods. Additionally, the cattle trade network was combined with a susceptible, infected, recovered (SIR) compartmental model to simulate spread of

SUBMITTER: Okello WO 

PROVIDER: S-EPMC8273440 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature