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Hybrid hyperalignment: A single high-dimensional model of shared information embedded in cortical patterns of response and functional connectivity.


ABSTRACT: Shared information content is represented across brains in idiosyncratic functional topographies. Hyperalignment addresses these idiosyncrasies by using neural responses to project individuals' brain data into a common model space while maintaining the geometric relationships between distinct patterns of activity or connectivity. The dimensions of this common model capture functional profiles that are shared across individuals such as cortical response profiles collected during a common time-locked stimulus presentation (e.g. movie viewing) or functional connectivity profiles. Hyperalignment can use either response-based or connectivity-based input data to derive transformations that project individuals' neural data from anatomical space into the common model space. Previously, only respon

SUBMITTER: Busch EL 

PROVIDER: S-EPMC8273921 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature