Telomere-to-telomere assembly of a fish Y chromosome reveals the origin of a young sex chromosome pair.

ABSTRACT:

Background

The origin of sex chromosomes requires the establishment of recombination suppression between the proto-sex chromosomes. In many fish species, the sex chromosome pair is homomorphic with a recent origin, providing species for studying how and why recombination suppression evolved in the initial stages of sex chromosome differentiation, but this requires accurate sequence assembly of the X and Y (or Z and W) chromosomes, which may be difficult if they are recently diverged.

Results

Here we produce a haplotype-resolved genome assembly of zig-zag eel (Mastacembelus armatus), an aquaculture fish, at the chromosomal scale. The diploid assembly is nearly gap-free, and in most chromosomes, we resolve the centromeric and subtelomeric heterochromatic sequences. In particul

SUBMITTER: Xue L 

PROVIDER: S-EPMC8273981 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature