Applying the Multiphase Optimization Strategy for the Development of Optimized Interventions in Palliative Care.

ABSTRACT: Recent systematic reviews and meta-analyses have reported positive benefit of multicomponent "bundled" palliative care interventions for patients and family caregivers while highlighting limitations in determining key elements and mechanisms of improvement. Traditional research approaches, such as the randomized controlled trial (RCT), typically treat interventions as "bundled" treatment packages, making it difficult to assess definitively which aspects of an intervention can be reduced or replaced or whether there are synergistic or antagonistic interactions between intervention components. Progressing toward palliative care interventions that are effective, efficient, and scalable will require new strategies and novel approaches. One such approach is the Multiphase Optimization Strategy

SUBMITTER: Wells RD 

PROVIDER: S-EPMC8274323 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature