Ontology highlight
ABSTRACT:
SUBMITTER: Hu Y
PROVIDER: S-EPMC8274441 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Hu Yoonsung Y Park Nogi N Seo Keun Seok KS Park Joo Youn JY Somarathne Radha P RP Olivier Alicia K AK Fitzkee Nicholas C NC Thornton Justin A JA
Virulence 20211201 1
<i>Streptococcus pneumoniae</i> (pneumococcus) is a normal colonizer of the human nasopharynx capable of causing serious invasive disease. Since colonization of the nasopharynx is a prerequisite for progression to invasive diseases, the development of future protein-based vaccines requires an understanding of the intimate interaction of bacterial adhesins with host receptors. In this study, we identified that pneumococcal surface adhesin A (PsaA), a highly conserved pneumococcal protein known to ...[more]