Dataset Information

Maculosin, a non-toxic antioxidant compound isolated from Streptomyces sp. KTM18.

ABSTRACT:

Context

Streptomyces species are prolific sources of bioactive secondary metabolites known especially for their antimicrobial and anticancer activities.

Objective

This study sought to isolate and characterize antioxidant molecules biosynthesized by Streptomyces sp. KTM18. The antioxidant potential of an isolated compound and its toxicity were accessed.

Materials and methods

The compound was purified using bioassay-guided chromatography techniques. Nuclear magnetic resonance (NMR) experiments were carried out for structure elucidation. The antioxidant potential of the isolated compound was determined using DPPH free radical scavenging assay. The toxicity of the isolated compound was measured using a brine shrimp lethality (BSL) assay.