Engineering biocompatible TeSex nano-alloys as a versatile theranostic nanoplatform.

ABSTRACT: Photothermal nanotheranostics, especially in the near infrared II (NIR-II) region, exhibits a great potential in precision and personalized medicine, owing to high tissue penetration of NIR-II light. The NIR-II-photothermal nanoplatforms with high biocompatibility as well as high photothermal effect are urgently needed but rarely reported so far. Te nanomaterials possess high absorbance to NIR-II light but also exhibit high cytotoxicity, impeding their biomedical applications. In this work, the controllable incorporation of biocompatible Se into the lattice of Te nanostructures is proposed to intrinsically tune their inherent cytotoxicity and enhance their biocompatibility, developing TeSex nano-alloys as a new kind of theranostic nanoplatforms. We have uncovered that the cytotoxicity of T

SUBMITTER: Ling X 

PROVIDER: S-EPMC8274553 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature