The impact of ossification spread on cervical spine function in patients with ossification of the posterior longitudinal ligament.

ABSTRACT: Ossification of the posterior longitudinal ligament (OPLL) is a progressive disease. The bridging of ossified lesions to the vertebral body gradually increases, thereby decreasing the mobility of the cervical spine; thus, cervical spine function may decrease over time. However, cervical spine function in patients with cervical OPLL has not been evaluated in large prospective studies. Therefore, we conducted a prospective multicenter study to clarify whether ossification spread can influence cervical spine function and quality of life (QOL) in patients with cervical OPLL. In total, 238 patients (162 men, 76 women; mean age, 63.9 years) were enrolled from 16 institutions. Each patient underwent whole spine computed tomography and was evaluated for cervical spine function and QOL using the Ja

SUBMITTER: Katsumi K 

PROVIDER: S-EPMC8275804 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature