New Secodaphnane-Type Alkaloids with Cytotoxic Activities from Daphniphyllum angustifolium Hutch.

ABSTRACT: One new Daphniphyllum alkaloid, daphnioldhanol A (1), together with three known ones, were isolated from the stem part of Daphniphyllum angustifolium Hutch. Their structures were elucidated by spectroscopic methods and comparing with the literature data. Compound 2 is a new natural product, but known by synthesis as a racemate. Compound 1 exhibited week cytotoxic activity against Hela cell line with IC₅₀ of 31.9 μM.

SUBMITTER: Lu QY 

PROVIDER: S-EPMC8275811 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature