Unknown

Dataset Information

0

New Secodaphnane-Type Alkaloids with Cytotoxic Activities from Daphniphyllum angustifolium Hutch.


ABSTRACT: One new Daphniphyllum alkaloid, daphnioldhanol A (1), together with three known ones, were isolated from the stem part of Daphniphyllum angustifolium Hutch. Their structures were elucidated by spectroscopic methods and comparing with the literature data. Compound 2 is a new natural product, but known by synthesis as a racemate. Compound 1 exhibited week cytotoxic activity against Hela cell line with IC50 of 31.9 μM.

SUBMITTER: Lu QY 

PROVIDER: S-EPMC8275811 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature

altmetric image

Publications

New Secodaphnane-Type Alkaloids with Cytotoxic Activities from Daphniphyllum angustifolium Hutch.

Lu Qing-Yun QY   Zhang Jia-Hui JH   Li Ying-Yao YY   Pu Xue-Xue XX   Zhang Cui-Shan CS   Liu Shuai S   Wan Jia-Jia JJ   Di Ying-Tong YT   Hao Xiao-Jiang XJ  

Natural products and bioprospecting 20210511 4


One new Daphniphyllum alkaloid, daphnioldhanol A (1), together with three known ones, were isolated from the stem part of Daphniphyllum angustifolium Hutch. Their structures were elucidated by spectroscopic methods and comparing with the literature data. Compound 2 is a new natural product, but known by synthesis as a racemate. Compound 1 exhibited week cytotoxic activity against Hela cell line with IC<sub>50</sub> of 31.9 μM. ...[more]

Similar Datasets

| S-EPMC6193994 | biostudies-literature
| S-EPMC6271962 | biostudies-literature
| S-EPMC4394112 | biostudies-literature
| S-EPMC4131615 | biostudies-literature
| S-EPMC8695325 | biostudies-literature
| S-EPMC6099570 | biostudies-literature
| S-EPMC6337136 | biostudies-literature
| S-EPMC3580017 | biostudies-literature
| S-EPMC8588253 | biostudies-literature
| S-EPMC11034800 | biostudies-literature