A longitudinal SARS-CoV-2 biorepository for COVID-19 survivors with and without post-acute sequelae.

ABSTRACT:

Background

SARS-CoV-2 has swept across the globe, causing millions of deaths worldwide. Though most survive, many experience symptoms of COVID-19 for months after acute infection. Successful prevention and treatment of acute COVID-19 infection and its associated sequelae is dependent on in-depth knowledge of viral pathology across the spectrum of patient phenotypes and physiologic responses. Longitudinal biobanking provides a valuable resource of clinically integrated, easily accessed, and quality-controlled samples for researchers to study differential multi-organ system responses to SARS-CoV-2 infection, post-acute sequelae of COVID-19 (PASC), and vaccination.

Methods

Adults with a history of a positive SARS-CoV-2 nasopharyngeal PCR are actively recruited from the communit

SUBMITTER: LaVergne SM 

PROVIDER: S-EPMC8276222 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature