Hypoactivation in the precuneus and posterior cingulate cortex during ambiguous decision making in individuals with HIV.

ABSTRACT: People with human immunodeficiency virus (HIV) often have neurocognitive impairment. People with HIV make riskier decisions when the outcome probabilities are known, and have abnormal neural architecture underlying risky decision making. However, ambiguous decision making, when the outcome probabilities are unknown, is more common in daily life, but the neural architecture underlying ambiguous decision making in people with HIV is unknown. Eighteen people with HIV and 20 controls completed a decision making task while undergoing functional magnetic resonance imaging scanning. Participants chose between a certain reward and uncertain reward with a known (risky) or unknown (ambiguous) probability of winning. There were three levels of risk: high, medium, and low. Ambiguous > risky brain acti

SUBMITTER: Hall SA 

PROVIDER: S-EPMC8276275 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature