Association Between Caseload Surge and COVID-19 Survival in 558 U.S. Hospitals, March to August 2020.

ABSTRACT:

Background

Several U.S. hospitals had surges in COVID-19 caseload, but their effect on COVID-19 survival rates remains unclear, especially independent of temporal changes in survival.

Objective

To determine the association between hospitals' severity-weighted COVID-19 caseload and COVID-19 mortality risk and identify effect modifiers of this relationship.

Design

Retrospective cohort study. (ClinicalTrials.gov: NCT04688372).

Setting

558 U.S. hospitals in the Premier Healthcare Database.

Participants

Adult COVID-19-coded inpatients admitted from March to August 2020 with discharge dispositions by October 2020.

Measurements

Each hospital-month was stratified by percentile rank on a surge index (a severity-weighted measure of COVID-19 caseload relativ

SUBMITTER: Kadri SS 

PROVIDER: S-EPMC8276718 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature