A data-driven functional mapping of the anterior temporal lobes.

ABSTRACT: Even though the anterior temporal lobe (ATL) comprises several anatomical and functional subdivisions, it is often reduced to a homogeneous theoretical entity, such as a domain-general convergence zone, or "hub", for semantic information. Methodological limitations are largely to blame for the imprecise mapping of function to structure in the ATL. There are two major obstacles to using fMRI to identify the precise functional organization of the ATL: the difficult choice of stimuli and tasks to activate, and dissociate, specific regions within the ATL and poor signal quality due to magnetic field distortions near the sinuses. To circumvent these difficulties, we developed a data-driven parcellation routine using resting-state fMRI data (24 females, 64 males) acquired using a sequence that w

SUBMITTER: Persichetti AS 

PROVIDER: S-EPMC8276737 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature